Anesthesia Technician Practice Exam

Which non-depolarizing muscle relaxant can be safely used in patients with malignant hyperthermia?

1. Vecuronium

2. Rocuronium

3. Succinylcholine

4. Both Vecuronium and Rocuronium

The correct answer is: Both Vecuronium and Rocuronium

The question addresses the safety of using non-depolarizing muscle relaxants in patients with malignant hyperthermia (MH), a life-threatening condition triggered by certain anesthetic agents, notably depolarizing muscle relaxants like succinylcholine. In the context of MH, non-depolarizing muscle relaxants, such as vecuronium and rocuronium, are preferred because they do not trigger the hypermetabolic process associated with MH. Both of these agents can be safely administered without risk of inducing or exacerbating a malignant hyperthermic episode, making them suitable alternatives during anesthesia for these at-risk patients. Vecuronium and rocuronium work by blocking acetylcholine at the neuromuscular junction without initiating the cascade of events that lead to MH. Thus, their use is advised in such clinical settings, which ensures patient safety and effective muscle relaxation during surgical procedures. On the other hand, succinylcholine, being a depolarizing agent, can precipitate an MH episode and is contraindicated in this population. This knowledge is essential for anesthesia technicians and practitioners, ensuring they make informed decisions in the operating room, particularly for patients with known susceptibility to malignant hyperthermia. Therefore, the correct response underscores the safety